Goals either side of half-time from Florian Wirtz and Robert Andrich gave Bayer Leverkusen a first-leg advantage in their Europa League semi-final at Roma.The newly-crowned Bundesliga winners and German Cup finalists, who recently overtook Juventus to claim the European record for the longest unbeaten streak across all competitions, lost 2-1 to Real Madrid in the 2002 Champions League final.